产品货号：
Z13004
中文名称：
CIITA抗体
英文名称：
Anti-CIITA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CIITA Antibody |
| 指标别名 | C2TA;CIITA;CIITAIV;MHC class II transactivator;MHC2TA;NLRA |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | CIITA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CIITA recombinant protein (Position:Y34-A1038). |
| 实际分子量 | 123KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CIITA is a human gene which is mapped to 16p13.This gene encodes a protein with an acidic transcriptional activation domain,4 LRRs (leucine-rich repeats) and a GTP binding domain.The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription,and is referred to as the "master control factor" for the expression of these genes.Also,the protein binds GTP and uses GTP binding to facilitate its own transport into the nucleus.Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion.Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency),increased susceptibility to rheumatoid arthritis,multiple sclerosis,and possibly myocardial infarction.Several transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P33076 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | class II major histocompatibility complex transactivator |
| 蛋白名全称 | MHC class II transactivator |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
相关搜索：CIITA抗体，CIITA多抗，Anti-CIITA Antibody